This letterbook covers the period February-May 1910. Most of the correspondence is by Edison, Harry F. Miller, and George A. Meister. Many of the letters pertain to laboratory work and supplies and to Edison's accounts with the Edison Portland Cement Co. and J. P. Morgan & Co. Also included is correspondence regarding ongoing developments in the fabrication of molds and patterns for use in the construction of concrete houses; Edison's search for a supply of bismuth; and the manufacture of his improved alkaline storage battery. Several letters describe the expected performance of Edison's battery on railway streetcars. Among the many items pertaining to family and personal matters is correspondence relating to Edison's health; his membership in clubs and societies; his charitable donations; and the upkeep of his winter home in Fort Myers, Florida. In addition, there are letters concerning Edison's opinion on the prohibition of alcohol and his suggestion for extracting the juice of discarded oranges, lemons, and grapefruits for use as citric acid, lemon oil, and "fruit sugar."

The label on the front cover contains the following notation: "Thomas A. Edison Personal  From February 7th 1910 to May 21, 1910." There is an inscription on the spine with similar information. The book contains 691 numbered pages and an index. Approximately 10 percent of the book has been selected.